ReTuBi Lecture - András Simon
On June 26 of 2017, András Simon, from Karolinska Institute, Department of Cell and Molecular Biology (Sweden) was the invited speaker as an expert visit for the "ReTuBi Lecture" with the talk “Salamander regeneration - regulation and evolution”.
Summary of the lecture:
The ability to regenerate lost body structures is present in diverse animal species ranging from simple organisms, such as the hydra to complex vertebrates, such as salamanders. We aim to understand how animals with outstanding regenerative capabilities sense what and how much is missing in relation to the normal homeostatic state, and how they translate that information to the appropriate regenerative responses. We primarily study an aquatic salamander, the newt, which possesses exceptional regenerative capacities among adult vertebrates. In particular, we focus on how progenitor cells are created and characterize their developmental potential during regeneration. We are currently generating comprehensive genetic resources such as transcriptome, genome databases, and in vivo genome editing tools for newts. We will use these genomic resources for gaining deeper insights into salamander regeneration at the molecular level and for cross-species comparisons with mammals in clinically relevant lesion/regeneration settings. Our research might reveal fundamental aspects of cell fate determination that could contribute to the design of novel regenerative strategies.
ReTuBi Lecture - Elodie Segura
On June 21 of 2017, Elodie Segura, from Institut Curie (France) was the invited speaker as an expert visit for the "ReTuBi Lecture" with the talk “Functional specialization of human dendritic cell subsets”.
Summary of the lecture:
Dendritic cells (DC) initiate and orient immune responses in lymphoid organs. DC are a heterogeneous population composed of several subsets with distinct phenotype and ontogeny. Mouse DC subsets have been shown to have distinct functions, especially in terms of antigen presentation and T cell stimulation. Whether the same is true for human DC subsets remains unclear. We have analyzed human DC directly purified from lymphoid organs and tissues, and found that some functional specializations are conserved between mouse and human DC, but others are not. These results have important implications for the rationale design of DC-based therapies.
Staff exchange between iMM-Curie (2017/06)
From June 18-23 of 2017, Inês Gomes, from Luís Costa Lab (iMM) made "ReTuBi Staff Exchange" to Marina Glukhova Lab (Institut Curie) to get new expertise in protocols for the isolation of mammary epithelial cells and the mammosphere assay serving to study the clonogenic potential of various mammary cell populations.
ReTuBi Lecture - Katie Bentley
On June 6 of 2017, Katie Bentley, from the Harvard Medical School (USA) was the invited speaker as an expert visit for the "ReTuBi Lecture" with the talk “Modelling endothelial cell behaviour in pathological angiogenesis”.
SINAL 2017 - 8th Meeting on Signal Transduction
The SINAL 2017 - 8th Meeting on Signal Transduction was held from June 1-2, 2017 at Pavilhão do Conhecimento, Lisbon. With circa 100 participants and 11 renown speakers, this meeting was focused on the following scientific topics:
- Cancer Cell Signaling
- Normal and aberrant signaling in the immune system
- Membrane Dynamics and Intracellular Signaling
- Spotlight on non-mammalian organisms
ReTuBi Summer School 2017
The ReTuBi Summer School was held from May 29 to 31, 2017 at the Oceanário de Lisboa and it was dedicated to the following scientific topics:
- Genetics and Epigenetics of Cancer
- Stem Cells and Cancer
- Cancer Microenvironment
- Cancer Metabolism
It also includes sessions with a FOCUS ON:
- Clinical trials in personalized medicine
- Systems Biology in Cancer
- How to write a research paper
With a total of 23 participants and 15 speakers, the ReTuBi Summer School was an excellent opportunity to PhD students and Postdcs researchers to get new insights in the cancer and tumour biology research area.