Staff exchange between iMM-DKFZ (2018/03)
From March 10 to 15 of 2018, Dalila Silva from Cláudio Franco Lab (iMM) made a “ReTuBi Staff Exchange” to Andreas Fischer Lab (DKFZ) to optimize a immunostaing protocol for a Notch antibody. During this staff exchange it was performed an immunostaing protocol in mice samples that involves several washes and incubations with antibodies. After this protocol it was produced some pictures using a confocal microscope (Carl Zeiss) that were analysed using the Fiji software. This exchange allowed to improve the quality images acquired.
From March 11 to 14 of 2018, Cláudio Franco Lab (iMM) made a “ReTuBi Staff Exchange” to Andreas Fischer Lab (DKFZ) to discuss the different projects ongoing in Andreas’ lab, to visit DKFZ core facilities to enhance the awareness on the latest technologies and capabilities available at DKFZ in order to seek convergence and cooperation opportunities between DKFZ and iMM.
Staff exchange between iMM-DKFZ (2018/02)
From February 03 to March 31 of 2018, Eunice Paisana from João Barata Lab (iMM) made a "ReTuBi Staff exchange" to Marc Remke lab (DKFZ). The aims of this staff exchange was to implement in João Barata Lab the CRISPR-Cas9 as a tool for knock down and knock out of genes and to perform high throughput screening of chemical compounds in cancer cell lines. During the staff exchange, Eunice Paisana start by learning the CRISPR-Cas9 technique in breast and colon cancer cell lines (MDA-MB-231 and HCT-116, respectively), both with and without brain tropism. After she modulated different genes that were found to be differentially expressed in samples from brain metastasis, in comparison with healthy tissues and primary tumors. Following this first aim, Eunice Paisana oerformed a drug screening using a clinical library including compounds approved by FDA (Food and Drugs Administration) or already in phase III and phase V clinical trials, allowing for the identification of potential therapies of patients with brain metastasis.
ReTuBi video presentation
The ReTuBi project is now on video! Please access iMM YouTube channel and please LIKE our video by giving it a thumbs up! Help us spread our project worldwide!
Career development and soft skills for young scientists (2 Edition)
It was held the “Second Edition of the Career development and soft skills for young scientists - from Lisbon to the World Workshop” from February 20 to 21 of 2018, at the Instituto de Medicina Molecular - João Lobo Antunes, Lisbon, Portugal. This Workshop was focused on career development and scientific integrity. The Workshop was planned with “General lectures” open to all scientific community and with “Hands-on sessions” for a target audience of 35 participants from Institut Curie, DKFZ and iMM.
The main objective of this Workshop was to provide to the participant’s the opportunity to discuss their career objectives and to exchange opinions with speakers about various career paths leading them away from the bench (education, industry, science communication and management). At the same time this Workshop provided contents related to responsible conduct of research in publication, research ethics, scientific integrity, scientific misconduct and good research practices.
School visits to iMM and ReTuBi labs
On January 17 and on February 8, 2018 two classes of 28 students each, visited iMM namely João Barata and Sérgio Dias labs, Biobank and the Electron Microscopy. The objective of this visit was to explain to students that through the ReTuBi project, the Instituto de Medicina Molecular (iMM) aims to fight cancer by reinforcing its capacity for outstanding pre-clinical and translational research, and by creating a dynamic cluster of excellence within the Lisbon region in the field of cancer research.
ReTuBi School Seminars - "The Biology of Cancer in one hour" (11/2017- 01/2018)
From November 2017 to January 2018, the ReTuBi project promoted several educational sessions entitled "The Biology of Cancer in one hour" addressed to the Secondary School students from the Biology course, in Lisbon. The following sessions were presented by the following researchers:
- Sérgio Dias - Secondary School D. Dinis - November 24, 2017
- Isabel Alcobia, from João Barata Lab - Secondary School of Lumiar - November 27, 2017
- Ana Rita Fragoso, from João Barata Lab - Secondary School Pedro Nunes - January 8, 2018
- Sandrina Nóbrega Pereira, from Sérgio Dias Lab - Secondary School Passos Manuel - January 9, 2018 and Secondary School de Camões - January 16, 2018
The main goal of these educational sessions is to present the iMM Lisboa research in the cancer and tumour biology area. The themes presented were focused on: What is cancer; Cell division; The repair mechanisms of DNA; Types of cancer; Which can lead to cancer; The properties of cancer; The role of the microenvironment and Carcinogenesis and new treatments.